李彩虹

李彩虹

学院： 基础医学院

专业： 生物化学与分子生物学

职称： 副教授

简介：

李彩虹，博士、硕导，广东医科大学生物化学与分子生物学副教授。兼任广东省生物化学与分子生物学学会第十一届理事会理事（2023-2028）。担任广东省自然科学各类项目评审专家。

长期从事天然活性物质抗肿瘤抗炎抗菌及其作用机制研究。目前主要研究方向为功能性食品理化性质、食品营养与慢性病、天然活性物质用于对虾等海产品保鲜及作用机制等。主持广东省自然科学基金1项，广东省中医药管理局科研基金2项，广东省医学科研基金、湛江市科研项目各1项、校级科研项目4项，作为项目组核心成员参与国家自然科学基金项目2项，主持广东省教育科学规划课题、广东省本科高校教学质量与教学改革工程项目、广东省协同育人校企合作项目等各1项。以第一作者或通讯作者发表科研论文44篇，其中SCI论文11篇，EI论文6篇、中文核心8篇等。获中国商业联合会科学技术一等奖（第2）和三等奖（第2）各1项，获广东省农业技术推广二等奖（第四）。

代表性成果:

1. Defeng Xu*, Caihong Li*, Mouming Zhao. Attenuation of UV-induced skin photoaging in rats by walnut protein hydrolysates is linked to the modulation of MAPK/AP-1 and TGF-β/Smad signaling pathways. Food Funct. 2022 Jan 24;13(2):609-623. doi: 10.1039/d1fo02598h. PMID: 34927661. （Top 一区，IF=6.317）

2. Defeng Xu, Weiqiong Wang, Jianmeng Liao, Lan Liao, Caihong Li*, Mouming Zhao*. Walnut proteins hydrolysates, rich with peptide fragments of WSREEQEREE and ADIYTEEAGR, ameliorate UV-induced photoaging through inhibition of NF-κB/MMP-1 signaling pathway in female rats[J]. Food & Function, 2020, 11:10601-10616. doi.org/10.1039/D0FO02027C (SCI 一区, IF=5.396)

3. Defeng Xu, Mouming Zhao, Haisheng Lin *, Caihong Li *. Theragra chalcogramma Hydrolysates, Rich in Gly-Leu-Pro-Ser-Tyr-Thr, Exerts Anti-Photoaging Potential via Targeting MAPK and NF-κB Pathways in SD Rats. Mar Drugs. 2022 Apr 24;20(5):286. doi: 10.3390/md20050286. PMID: 35621937; PMCID: PMC9144478.（SCI 医学大类 二区，IF=6.085）

4. Xu D, Li C, Zhao M. Theragra chalcogramma Hydrolysate, Rich in Gly-Leu-Pro-Ser-Tyr-Thr, Alleviates Photoaging via Modulating Deposition of Collagen Fibers and Restoration of Extracellular Components Matrix in SD Rats. Mar Drugs. 2022 Apr 1;20(4):252. doi: 10.3390/md20040252. PMID: 35447925; PMCID: PMC9028377. （SCI 医学大类 二区，IF=6.085）

5. Defeng Xu, Lijun Sun*, Caihong Li*, Yaling Wang, Riying Ye. Inhibitory effect of glucose oxidase from Bacillus sp. CAMT22370 on the quality deterioration of Pacific white shrimp during cold storage[J]. LWT-Food Science and Technology, 2018, 92: 339-346. (SCI二区，IF:3.714)

6. Xu D, Zheng X, Li C*, Wu J, Sun L, Qin X, Fan X. Insights into the response mechanism of Litopenaeus vannamei exposed to cold stress during live transport combining untargeted metabolomics and biochemical assays. J Therm Biol. 2022 Feb;104:103200. doi: 10.1016/j.jtherbio.2022.103200. Epub 2022 Jan 26. PMID: 35180976.（SCI 生物学大类三区，IF=3.189）

7. Kai Yao#, Jingjing Shao#, Keyuan Zhou, Haitao Qiu,  Fengxiang Cao,  Caihong Li*, De Dai*. Grape seed proanthocyanidins induce apoptosis through the mitochondrial pathway in nasopharyngeal carcinoma CNE-2 cells[J]. Oncology Reports, 2016, 36: 771-778. (SCI三区，IF:3.041)

8. Cui ZY#, Li CH#, Li XY, Zhang QZ, Zhang YF, Shao JJ, Zhou KY*.Sodium selenite (Na2SeO3) induces apoptosis through the mitochondrial pathway in CNE-2 nasopharyngeal carcinoma cells [J]. International Journal of Oncology,2015, 46: 2506-2514. (SCI 三区，IF:3.571)

9. Caihong Li, Defeng Xu*, Mouming Zhao, Lijun Sun, Yaling Wang. Production optimization, purification and characterization of a novel acid protease from a fusant by Aspergillus oryzae and Aspergillus niger[J]. European food research and technology, 2014, 238(6): 905-917. (SCI 三区，IF：2.056)

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