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孙艳芹

2023年09月17日 09:35  点击:[]

孙艳芹

学院:基础医学院

专业:病理学

职称:副教授

简介:

孙艳芹(Yanqin Sun),临床肿瘤学博士,病理学硕士研究生导师(学术型、专业型),东莞市特色人才,东莞创新研究院副院长(顶岗)。兼任广东省科学学与科技管理研究会医学研究专业委员会常务委员、广东省医学教育协会肿瘤学专业委员会委员。

主要从事小细胞肺癌临床化疗耐药的分子机制研究。获国家自然科学基金委、广东省科技厅、广东省卫健委及湛江市科技局等科研基金资助。以第一作者或通讯作者发表多篇学术论文。

【科研项目】

1.国家‒自然科学基金委青年基金(81702285),2018-2020,主持

2.广东省‒自然科学基金面上项目(2017A030313644),2017-2020,主持

3.广东省‒自然科学基金面上项目(2016A030313822),2016-2019,主持

4.广东省‒自然科学基金粤莞区域联合基金(2021B1515140067),2021-2024,主持

5.广东省‒自然科学基金面上项目(2022A1515012190),2022-2024,主持

6.广东省‒医学科研基金(A2022019),2022-2024,主持

7.广东省‒医学科研基金(A2017330),2017-2019,主持

8.湛江市科技发展专项资金竞争性分配项目(2022A01018),2021-2024,主持

【代表性成果】

  1. Sun Y#;Zhou Y#;Bai Y#;Wang Q;Bao J;Luo Y;Guo Y*;Guo L*;A long non-coding RNA HOTTIP expression is associated with disease progression and predicts outcome in small cell lung cancer patients,Mol Cancer,2017,16(1):162.

  2. Sun Y#;Hu B#;Wang Q#;Ye M;Qiu Q;Zhou Y;Zeng F;Zhang X;Guo Y*;Guo L*;Long non-coding RNA HOTTIP promotes BCL-2 expression and induces chemoresistance in small cell lung cancer by sponging miR-216a,Cell Death Dis, 2018,9(2):85.

  3. Sun Y;ZengC;GanS;LiH;ChengY;ChenD;LiR;ZhuW*;LncRNA HOTTIP-Mediated HOXA11 Expression Promotes Cell Growth, Migration and Inhibits Cell Apoptosis in Breast Cancer,Int J Mol Sci, 2018, 19(2). pii: E472.

  4. Sun Y#;Hu B#;Wang Y;Li Z;Wu J;Yang Y;Wei Y;Peng X;Chen H;Chen R;Jiang P;Fang S;Yu Z;Guo L*;miR-216a-5p inhibits malignant progression in small cell lung cancer: involvement of the Bcl-2 family proteins,Cancer Manag Res,2018,10:4735-4745.

  5. Gan S, Dai H, Li R,Liu W, Ye R, Ha Y, Di X, Hu W, Zhang Z,Sun Y*.Identification of key differentially expressed genes between ER-positive/HER2-negative breast cancer and ER-negative/HER2-negative breast cancer using integrated bioinformatics analysis.Gland Surg,2020,9(3): 661–675.

  6. Sun Y#;Long J#;Yin Y;Li H;Jiang E;ZengC;Zhu W*;Characterization of CSF2A fusion gene andits effect on Epstein-Barr virus-positive tumor cells,J. Med. Virol, 2018, 90(11).

  7. Zhu W#;Long J#;Yin Y;Guo H;Jiang E;Li Y;He Q;Zeng C*;Sun Y*;MicroRNA-34a suppresses the invasion and migration of colorectal cancer cells by enhancing EGR1 and inhibiting vimentin,Exp Ther Med, 2019, 18(4):2459-2466.

  8. Sun Y#, Yi Y#, Gan S#, Ye R#, Huang C, Li M, Huang J*, Guo Y*.miR-574-5p mediates epithelial-mesenchymal transition in small cell lung cancer by targeting vimentin via a competitive endogenous RNA network.Oncol Lett.2021 Jun;21(6):459.

  9. Ye R#, Tang R#, Gan S#, Li R, Cheng Y, Guo L, Zeng*,Sun Y*.New insights into long non-coding RNAs in non-small cell lung cancer.Biomed Pharmacother. 2020 Nov;131:110775.Erratum in: Biomed Pharmacother. 2020 Dec;132:110930.

  10. Cai K#, Xie Z#, Liu Y#, Wu J, Song H, Liu W, Wang X, Xiong Y*., Gan S*,Sun Y*.Identification of Potential Key Genes and Prognostic Biomarkers of Lung Cancer Based on Bioinformatics.Biomed Res Int. 2023 Jan 18;2023:2152432.

  11. Song H#, Wu J#, Liu W#, Cai K, Xie Z, Liu Y, Huang J, Gan S*, Xiong Y*,Sun Y*.Key genes involved with prognosis were identified in lung adenocarcinoma by integrated bioinformatics analysis.Heliyon. 2023 May 29;9(6):e16789.

  12. 黄彩玲,甘思远,刘旺,蔡凯尔,宋浩,舒旭,何志巍*,孙艳芹*.EZH2在小细胞肺癌恶性表型中的作用及其潜在调控机制[J].临床与实验病理学杂志,2022,38(10):1170-1176.(中文核心)

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