衣艳梅,医学博士,教授,硕士研究生导师。2010年毕业于中山大学微生物与生化药学专业,获博士学位。2010.7入职广东医科大学。2019.7-2020.12国家公派至路易斯维尔大学医学院学习。现为广东省抗癌协会肿瘤转移专业委员会委员,国家自然科学基金、广东省自然科学基金通讯评审。
本人近年来一直从事肿瘤微环境在肿瘤发生发展及治疗耐受中的作用研究,包括:①非小细胞肺癌EGFR-TKIs耐药机制的研究;②肿瘤代谢重编程在肿瘤发生发展中的作用研究等。主持国家自然科学基金2项(已结题1项),广东省自然科学基金2项,广东省医学科研基金1项,广东医科大学校级重点项目2项,参与多项国家级、省部级课题研究。以第一及通讯作者在国内外期刊发表学术论文多篇,指导硕士研究生多名。
Yanmei Yi; Pan Li; Yuanfeng Huang; Danyang Chen; Siwen Fan; Jun Wang; Minqiang Yang; Shanshan Zeng; Jin Deng; Xinwu Lv; Kai Luo; Zhiwei He; Hao Liu.P21-activated kinase 2-mediatedβ-catenin signaling promotes cancer stemness and osimertinib resistance in EGFR-mutant non-small cell lung cancer. Oncogene, 2022, 41(37): 4318-4329.
Danyang Chen; Siwen Fan; Jun Wang; Yanqing Liang; Pan Li; Xinwu Lv; Yanqin Sun; Qian Wang; Hao Liu; Chuantao Zhang;Yanmei Yi*.Cip2a induces arginine biosynthesis and promotes tumor progression in non‐small cell lung cancer, Molecular Carcinogenesis, 2023,62(4):561-572.
Fan Zhang,Pan Li,Shuang Liu,Mingqiang Yang,Shanshan Zeng,Junjian Deng,Danyang Chen,Yanmei Yi*,Hao Liu.b-Catenin-CCL2 feedback loop mediates crosstalk between cancer cells and macrophages that regulates breast cancer stem cells.Oncogene,2021,40(39):5854-5865.
Rong Jin,Jiaqing Hao,Yanmei Yi,Di Yin,Yuan Hua,Xiaohong Li,Hanmei Bao,Xianlin Han,Nejat K Egilmez,Edward R Sauter,Bing Li. Dietary Fats High in Linoleic Acids Impair Antitumor T-cell Responses by Inducing E-FABP-Mediated Mitochondrial Dysfunction. Cancer Res, 2021, 81(20): 5296-5310.
Rong Jin,Jiaqing Hao,Yanmei Yi,Edward Sauter,Bing Li.Regulation of macrophage functions by FABP-mediated inflammatory and metabolic pathways. BBA-Mol Cell Biol Lipids, 2021;1866(8): 158964-158973.
Yuwen He,Danyang Chen,Yanmei Yi#,Shanshan Zeng,Shuang Liu,Pan Li,Hui Xie,Pengjiu Yu,Guanmin Jiang,Hao Liu. Histone Deacetylase Inhibitor Sensitizes ERCC1-High Non-small-Cell Lung Cancer Cells to Cisplatin via Regulating miR-149. Mol Ther Oncolytics,2020, 17:448-459.
Minhua Wu, Yanqin Sun, Feipeng Xu, Yanqing Liang, Hao Liu,Yanmei Yi*. Annexin A2 Silencing Inhibits Proliferation and Epithelial-to-mesenchymal Transition through p53-Dependent Pathway in NSCLCs. J Cancer,2019, 10(5): 1077-1085.
Yanmei Yi, Shanshan Zeng, Zhaotong Wang, Minhua Wu, Yuanhuan Ma, Xiaoxia Ye, Biao Zhang, Hao Liu.Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signaling.BBA-Mol Basis Dis, 2018,1864(3):793-803.